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更新于 今天

DMPK Senior Scientist

2-3萬
  • 北京昌平區(qū)
  • 1-3年
  • 博士
  • 全職
  • 招1人

職位描述

DMPK質(zhì)譜
We are seeking a senior DMPK scientist
who can play a leading role in driving DMPK strategies as a program
representative for projects from early discovery through to the clinic. The
qualified candidate must possess comprehensive knowledge of both in vitro and
in vivo ADME and pharmacokinetics. Being capable of representing DMPK
functional on multidisciplinary project teams and being responsible for
progressing molecules with appropriate ADME properties through lead
optimization to clinical candidate nomination is essential.
Qualifications
Required Experience and Skills
  1. A Ph.D. in Pharmaceutical Sciences, Chemistry, Engineering, or related field. 1~3 years of relevant industry experience is required.
  2. A strong understanding of ADME and pharmacokinetic principles and experience in supporting drug discovery and development as a DMPK project representative
  3. Broad understanding of various DMPK-relevant areas such as physicochemical properties, drug-metabolizing enzymes, drug-drug interactions, and qualitative and quantitative bioanalytical techniques.
  1. Ability to translate data into project relevance, as part of anticipating and
    mitigating program challenges, is required.
  2. Experience in M&S tools such as Phoenix, WNL, and Gastroplus is a plus.
  3. Excellent interpersonal and organizational skills with a can-do attitude.
  4. Good communication skills in both oral and written forms are
essential.
Job Duties:
1.The candidate will join a collaborative, multidisciplinary team working closely with other research groups at Sironax, including Medicinal Chemistry, Biology,
Pharmacology, and Toxicology.
2. Ability to formulate program DMPK strategy from hit to candidate selection and ensure project ADME challenges are thoroughly assessed and resolved.
3. Analyzing DMPK experimental data to project teams, functional leaders, and other key stakeholders to ensure alignment and influence decisions, and help understand complex DMPK-related issues.
4 Providing disciplinary scientific leadership and mentorship for junior scientists.

工作地點(diǎn)

玉河南路(中關(guān)村生命科學(xué)園)北京市昌平區(qū)生命科學(xué)園醫(yī)科路9號(hào)院2號(hào)樓9層

職位發(fā)布者

王女士/HR Manager

剛剛活躍
立即溝通
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維泰瑞?。ū本┥锟萍加邢薰臼且患胰蛐缘膶W⒂谘邪l(fā)First-in-class化學(xué)藥物的生物制藥公司。該公司由北京生命科學(xué)研究所的所長,美國科學(xué)院院士,中國科學(xué)院外籍院士王曉東博士和北京生命科學(xué)研究所資深研究員張志遠(yuǎn)博士共同創(chuàng)建。公司坐落在昌平區(qū)中關(guān)村生命科學(xué)園。本公司針對(duì)王曉東博士在細(xì)胞凋亡、細(xì)胞程序性壞死等多種細(xì)胞死亡領(lǐng)域的原創(chuàng)性發(fā)現(xiàn)研發(fā)小分子抑制劑,致力于多種重大疾病的治療。這些抑制劑針對(duì)的疾病包括神經(jīng)退行性疾病如阿爾茲海默癥、多發(fā)性硬化癥、帕金森病等;缺血性疾病如腦卒中、腎缺血、心肌缺血;以及炎癥性疾病如腸炎、銀屑病、膿毒癥等。本公司研發(fā)能力涵蓋小分子篩選,化學(xué)合成,分子、細(xì)胞生物學(xué)研究,動(dòng)物藥效評(píng)價(jià),藥代藥動(dòng)分析及臨床前預(yù)毒理分析等藥物研發(fā)的所有環(huán)節(jié)。本公司的研發(fā)團(tuán)隊(duì)由王曉東博士和張志遠(yuǎn)博士直接領(lǐng)導(dǎo),團(tuán)隊(duì)主要成員均具備十年以上科學(xué)研究經(jīng)驗(yàn),前期科研成果均發(fā)表在國際頂級(jí)學(xué)術(shù)刊物如,Cell,Molecular Cell, eLife,PNAS等。本公司的管理團(tuán)隊(duì)均具備數(shù)十年國際制藥企業(yè)的管理經(jīng)驗(yàn),曾成功推動(dòng)多個(gè)藥物進(jìn)入臨床實(shí)驗(yàn)和上市使用。公司福利待遇:對(duì)于優(yōu)秀博士公司有機(jī)會(huì)解決北京戶口問題;公司設(shè)有博士后工作站。
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